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Probiotics

Updated: 2025-10-08

In brief

Probiotics are live microorganisms (often Lactobacillus, Bifidobacterium, or Saccharomyces boulardii) that support gut flora balance and contribute to digestive health.
👉 Their effectiveness depends on the strain, dosage, and duration of use.

🟢 What it does (main evidence)

  • Post-antibiotic diarrhea: strong evidence, especially with S. boulardii and L. rhamnosus GG.
  • IBS (Irritable Bowel Syndrome): moderate improvement in pain and bloating (strain-dependent).
  • Intestinal infections / irregular transit: reduced recurrence risk in several trials.
  • Gut immune health: some strains support healthy intestinal permeability and mucosal defenses.

🟡 What’s unclear

  • Results are highly strain-specific — a “multi-strain” product isn’t automatically better.
  • Effects may take 4–8 weeks to appear.
  • Benefits often fade after discontinuation.

🔴 What it doesn’t do

  • Does not “detoxify” the body.
  • No proven effect on weight loss or chronic fatigue.
  • Not a substitute for antibiotics or treatment for autoimmune diseases.

Dosage & usage (non-prescriptive)

  • 5–20 billion CFU/day, 1–2 servings depending on tolerance.
  • Trial period of 4–8 weeks before evaluation.
  • Take away from antibiotics (≥ 2 h).
  • Store cool and dry, per manufacturer guidance.

Safety

  • Generally well tolerated.
  • May cause temporary bloating during the first few days.
  • Use caution with severe immunodeficiency, heart prosthesis, or systemic infection (rare but documented risk).

Risks & interactions

  • May cause temporary bloating at first; use caution in immunocompromised individuals.
  • Take 2h apart from antibiotics; some strains may interact with autoimmune conditions.

Quality tips

  • Check:
    • Exact strain (e.g., Lactobacillus rhamnosus GG).
    • Viable count (CFU) at expiration date.
    • Storage conditions (refrigerated or shelf-stable).
  • Prefer brands with COA / viability testing and transparent strain labeling.
  • Avoid “detox” products lacking scientific evidence.

Sources

- https://ods.od.nih.gov/ - https://examine.com/supplements/probiotics/ - https://www.canada.ca/en/health-canada.html
  • Examine.com — Probiotics Overview
  • NIH/ODS — Gut Health & Microbiome
  • Health Canada — Natural Health Products: Digestive Category
⚠️ Educational information. Always seek professional advice.