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Panthenol (Vitamin B5) Cream

Updated: 2025-12-09

In brief

Panthenol (vitamin B5) is a core skin-repair ingredient.
👉 Particularly useful for soothing, hydrating, and restoring the skin barrier.
👉 Its tolerance profile is excellent, even on compromised skin.

🟢 What it does (main evidence)

  • Strengthens the skin barrier.
  • Soothes redness and irritation.
  • Improves hydration and comfort.
  • Supports recovery after active treatments.

🟡 What is unclear

  • Direct anti-aging effects are limited.
  • Results depend on overall formulation quality.

🔴 What it does NOT do

  • Does not erase deep wrinkles.
  • Does not replace sunscreen.
  • Is not an exfoliating or brightening agent.

Concentrations & forms

  • 1–2%: hydration and soothing.
  • 2–5%: enhanced repair and barrier support.

💣 Practical upper limit

Note: concentrations above $≈ 1–5% (panthenol) rarely improve results
and may affect cosmetic feel.

Safety

  • Very well tolerated.
  • Suitable for daily use, morning and night.

Practical usage tips

  • Apply after active serums.
  • Ideal post-retinol or post-exfoliation.

Sources

- https://pubmed.ncbi.nlm.nih.gov/ - https://www.aad.org/ - https://www.ncbi.nlm.nih.gov/books/
⚠️ Educational information. Always seek professional advice.