Panthenol (Vitamin B5) Cream
Updated: 2025-12-09
In brief
Panthenol (vitamin B5) is a core skin-repair ingredient.
👉 Particularly useful for soothing, hydrating, and restoring the skin barrier.
👉 Its tolerance profile is excellent, even on compromised skin.
🟢 What it does (main evidence)
- Strengthens the skin barrier.
- Soothes redness and irritation.
- Improves hydration and comfort.
- Supports recovery after active treatments.
🟡 What is unclear
- Direct anti-aging effects are limited.
- Results depend on overall formulation quality.
🔴 What it does NOT do
- Does not erase deep wrinkles.
- Does not replace sunscreen.
- Is not an exfoliating or brightening agent.
Concentrations & forms
- 1–2%: hydration and soothing.
- 2–5%: enhanced repair and barrier support.
💣 Practical upper limit
Note: concentrations above $≈ 1–5% (panthenol) rarely improve results
and may affect cosmetic feel.
Safety
- Very well tolerated.
- Suitable for daily use, morning and night.
Practical usage tips
- Apply after active serums.
- Ideal post-retinol or post-exfoliation.
Sources
- https://pubmed.ncbi.nlm.nih.gov/ - https://www.aad.org/ - https://www.ncbi.nlm.nih.gov/books/
⚠️ Educational information. Always seek professional advice.