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Niacinamide (Vitamin B3) Cream

Updated: 2025-12-09

In brief

Niacinamide (vitamin B3) is one of the most versatile and well-tolerated skincare ingredients.
👉 It supports the skin barrier, oil balance, and even skin tone.
👉 Benefits are gradual but consistent.

🟢 What it does (main evidence)

  • Strengthens the skin barrier.
  • Helps regulate sebum production.
  • Reduces redness and inflammation.
  • Improves overall skin tone.

🟡 What is unclear

  • Direct anti-aging effects are modest.
  • Results depend on formulation quality.

🔴 What it does NOT do

  • Does not remove deep wrinkles.
  • Does not replace sunscreen.
  • Does not treat severe acne on its own.

Concentrations & forms

  • 2–5%: effective and well tolerated.
  • 5–10%: stronger effects, higher irritation risk.

💣 Practical upper limit

Note: concentrations above $≈ 5–10% (niacinamide) rarely improve results
but may reduce tolerability.

Safety

  • Suitable for most skin types.
  • Can be used morning and/or night.

Practical usage tips

  • Apply before moisturizer.
  • Works well with hyaluronic acid and ceramides.

Sources

- https://pubmed.ncbi.nlm.nih.gov/ - https://www.aad.org/ - https://www.ncbi.nlm.nih.gov/books/
⚠️ Educational information. Always seek professional advice.